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KMID : 0381219760080050319
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Journal of RIMSK
1976 Volume.8 No. 5 p.319 ~ p.320
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Clinical Histopathology Note
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박일진/Park, I.C.
서덕규/박태수/안부호/Suh, D.K./Park, T.S./Ahn, B.H.
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Abstract
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A 3-year-old Korean male baby was admitted, because of loss of appetites, mild fever and loss of bowel habitus. He experienced a physical trauma 15 days ago, and the hematoma was not reabsorbed. until admission. On physical examination, a pale baby represented generalized petechia and edema on the both eyelids.
Pancytopenia (Hb, 4.0 gm/dl; WBC, 2, 650/mm3; and platelates, 73, 000/mm3) with predominance of lymphocytes (92%) and the number of reticulocytes were 1. 5% -On bone
marrow examination, marked increase in number of lymphocytes and lymphoblasts (46% of all nucleated cells) were found and 93% of all nucleated cells were reactive for periodic-acid-Schiff´s reaction and less than 1% of all nucleated cells are reactive for peroxidase reaction.
Several special tests were performed and the followings were ensued;
1) Rosette test for thymus-dependent lymphocytes; 12.5%.
2) Fluorescent microscopy for marrow-derivated lymphocytes; 75%.
3) Radial immunodiffusion with tripartigen plate (Behringwerke Co.)for immunoglobulin ananlysis; IgG 950 mg/dl, IgA 140 mg/dl and IgM 92 mg/dl.
As a summary, we made the diagnosis as acute undifferentiated lymphocytic leukemia and it could be suspected that those neoplastic proliferation might be originated from B-cell alone.
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